Penile Nerve Neuromodulation

In cases where traditional methods (medication, creams, or psychotherapy) are insufficient for treating premature ejaculation, the source of the problem is often hereditary or structural hypersensitivity of the nerve endings in the glans penis. Penile nerve neuromodulation is an advanced surgical approach that permanently optimizes this hypersensitivity, giving the man control over ejaculation. At Uro Health Clinic, we perform this procedure to world standards with our academic expertise and microsurgical precision.

What is Penile Nerve Neuromodulation?

Neuromodulation, in its simplest definition, is the process of balancing excessive stimuli in the nervous system through surgical or electrical methods. In urological applications, this method is used to slow down excessively rapid ejaculation signals traveling from the glans penis to the brain.

This procedure is based on the principle of examining the dorsal nerves (nerves on the back of the penis) that provide sensation, using microsurgical techniques, and controlling and adjusting the branches that cause hypersensitivity. Also known as “Selective Dorsal Neurotomy,” this procedure reduces only the “unavoidable” sensitivity that triggers ejaculation, without impairing the normal sensation of the penis or the quality of erection. In our clinic, an anatomical nerve map of the patient is created, and only the necessary branches are intervened upon.

Advanced Laser Technology

Precise and minimally invasive surgery with next-generation lasers.

Minimal Pain

Less bleeding, a more comfortable and safer treatment process.

Fast Recovery

Short hospital stay and quick return to daily life.

Expert Urology Team

Safe surgery with experienced physicians and advanced technology.

Who is it suitable for? (Patient Selection)

Not every case of premature ejaculation requires surgery; however, for some patients, neuromodulation is the only permanent solution. Performing the right procedure on the right patient is the most critical step in the success of the operation.

Patients who meet the following criteria are particularly strong candidates for neuromodulation:

Those who have experienced (primary) chronic premature ejaculation problems since their first sexual experience,
Those who do not respond to drug treatments (SSRI group) or who want to avoid drug side effects,
Those who achieve a temporary extension of erection with glans penis fillers or local anesthetic creams (which confirms nerve sensitivity),
Individuals whose ejaculation time is less than 1 minute without any physical obstruction.

Microsurgical Methods and Technical Details

The penile nerve structure is an extremely complex network, measured in millimeters. Therefore, neuromodulation procedures should only be performed under high-magnification microscopes and by surgeons specializing in this field.

This technique, which we perform in our modern operating rooms at Zorlu Center, takes approximately 45-60 minutes. A small incision is made at the base of the penis to access the nerve networks. Using devices that measure nerve conduction, we identify which nerve fibers are “overactive” and selectively modulate them. Through this delicate balance, we aim to increase ejaculation time by 5 to 10 times without experiencing a loss of sexual pleasure.

Recovery Process and Post-Operative Expectations

Neuromodulation is a procedure that does not require a long hospital stay and has a very high recovery rate. Our patients can return to their social lives immediately after the operation.

The procedure is usually performed under general anesthesia or sedation, so the patient feels no pain. Mild swelling and tightness in the area are normal for a few days after the operation. The stitches are self-dissolving, so there is no need for stitch removal. A waiting period of 4 weeks is generally recommended for full recovery and return to sexual activity. At the end of this period, patients begin to notice that, for the first time in their lives, they are able to control their ejaculation reflex voluntarily.

Why Neuromodulation at Uro Health Clinic?

Neurosurgery is a field that does not tolerate errors and requires a combination of military discipline and academic knowledge. Uro Health Clinic is one of the leading boutique clinics in Türkiye that performs this specific operation with the highest success rate. At our prestigious facility in Zorlu Center, we offer not just an operation, but a transformative process where our patients regain their sexual confidence. Our physicians, all with academic qualifications, treat each patient as an individual case, maintaining transparent communication at every step, from pre-operative testing to post-operative follow-up. With our principle of confidentiality and professional team, we are here to provide you with the most modern and lasting solutions for your urological health.

Penile Nerve Neuromodulation - Frequently Asked Questions

1. What is penile nerve neuromodulation and how does it work?

This method is a microsurgical procedure that permanently optimizes hypersensitivity in the glans penis. Overactive nerve branches that transmit ejaculation signals to the brain too quickly are selectively regulated, thus allowing the ejaculation reflex to be controlled by the individual. At Urohealth, we recommend that every man over 40 undergo regular urological checkups and PSA tests at least once a year.

2. Will I experience any loss of sexual pleasure or sensation after this procedure?

No. The operation is a “selective” method. Only the hypersensitive branches that cause premature ejaculation are targeted. The penis’s normal sensation of touch and its capacity for sexual pleasure are fully preserved.

3. Does surgery affect erection quality?

Absolutely not. Only the nerves that transmit sensation are affected. The blood vessels and nerve structures responsible for erection are located in different parts of the penis and are not touched during this operation.

4. Who are the most suitable candidates for this operation?

This is the most definitive and permanent solution, especially for patients who have experienced chronic premature ejaculation since puberty, have not responded to drug treatments (SSRIs, etc.), or do not want to use medication/creams for life.

5. How long does the operation take and is anesthesia necessary?

The procedure is usually performed under general anesthesia or sedation for the patient’s comfort. The operation, performed with microsurgical precision, takes approximately 45-60 minutes.

6. Will there be scarring after the surgery?

The operation is performed through a very small incision at the base of the penis. Because aesthetic sutures and dissolvable threads are used, there is no noticeable scarring after healing, and there is no need for stitches to be removed.

7. How long does the recovery process take and when will I be discharged?

It is a procedure that does not require hospitalization and has a high recovery rate. Our patients are usually discharged the same day and can return to their social lives within a few days.

8. When can I resume sexual activity?

To allow the nerve structure and suture line to heal completely, a period of sexual abstinence for 4 weeks is generally recommended after the operation.

9. Is the success of this method permanent?

Yes. Unlike medications or creams, neuromodulation provides a structural regulation, so its effects are lifelong. The goal is to increase ejaculation time by 5 to 10 times, depending on the patient’s condition.

10. Why should I get neuromodulation treatment at Urohealth Clinic?

Neurosurgery does not tolerate mistakes. At Urohealth Clinic, with our high-magnification microscopes and academic expertise, we are one of the centers in Türkiye that performs this specific operation with the highest success rate. We offer complete confidentiality and professionalism in our prestigious environment at Zorlu Center.